The placeholders bug (see this distribution's RT bugs) renders this module useless for serious applications. The patch to fix this is trivial, so it's a shame that the author doesn't seem to be interested in updating the module.
I also had no luck getting mysqlPP to work with my MovableType installation (in fact, some table values were overwritten with NULLs when I tried). To be fair, I don't know if it's a problem with the module or MovableType wanting to do lots of DBD-specific things.
Anyway, keep your eyes open when attempting to use this module as a drop-in replacement for DBD::mysql on your webserver..