If you insist on doing The Next Big Thing in Perl, go ahead and plow through wx, Gtk2, FLTK, or even Tk. Like many folks, I've no time (or skill) to dig deeper, so I'll leave expert judgement to the experts, but if you have a "Perlish job" to do, (i.e. it needs to be done before lunch), look no further. Laziness, impatience, and hubris, (and the genius required to instantiate them simultaneously), are all here. Highly recommended.